Sodium Thiosulfate USP NF BP Ph Eur Reagent FCC Manufacturers

Anmol Chemicals is the pioneer manufacturers of Sodium Compounds, Pharmaceutical Excipients Fragrance Food & Flavor chemicals in India. We offer Halal and Kosher Sodium Compounds made in an ISO9001, ISO22000 (FSSC22000), GLP and cGMP certified facility. Our group has several manufacturing facilities spread across the world, supported by toll manufacturers and representatives in UAE, Europe, Africa, USA, China and has several associated manufacturing facilities spread across India. All the Information on Physics, Chemistry, Applications, Uses and Technology on Manufacture of Sodium Thiosulfate Pentahydrate Anhydrous is in these pages.

The units have one or more of the certifications like FDA GMP, ISO 9001, ISO 22000, HACCP, REACH, Kosher & Halal

Sodium Thiosulfate Pentahydrate Anhydrous USP NF BP Ph Eur Reagent FCC Food Grade Manufacturers Exporters

Sodium Thiosulfate CAS Number 10102-17-7 for pentahydrate and 7772-98-7 for anhydrous, EINECS EC Number: 231-867-5, Molecular Weight 248.17 for pentahydrate and 158.11 for anhydrous, Chemical Formula Na2S2O3.5H2O for pentahydrate and Na2S2O3 for anhydrous.

Specifications of Sodium Thiosulfate Pentahydrate Crystals:
Appearance: Cylindrical Pellets (5 mm to 10 mm for size P4) & (2 mm to 5 mm for size P8)
pH of 10% Aqueous Solution: 6.5 to 8
Assay: 99.5% minimum
Sulphites & Sulphates: 0.2% maximum.
Heavy Metals: 3 ppm maximum.
Iron: 5 ppm maximum.

Specifications of Sodium Thiosulfate Anhydrous:
Assay as (Na2)S2O3: 98 % minimum.
10% solution in water: Clear
Description: White powder free from foreign particles.
pH of 10 % Solution: 6.5 To 8.5
Sulphites & Sulphates: 0.5% maximum
Iron: 10 ppm maximum.
Heavy Metals: 10 ppm maximum.

Contains not less than 99.0 percent and not more than 100.5 percent of Na2S2O3, calculated on the anhydrous basis.

Identification:
A: To a solution (1 in 10) add a few drops of iodine TS: the color is discharged.
B: A solution (1 in 10) responds to the tests for Sodium and for Thiosulfate.

Water: Dry about 1.0 g, accurately weighed, in vacuum at 40 o to 45o for 16 hours: it loses between 32.0% and 37.0% of its weight.
Calcium: Dissolve 1 g Sodium Thiosulfate in 20 mL of water, and add a few mL of ammonium oxalate TS: no turbidity is produced.
Heavy metals: the limit is 0.002%.

CHARACTERS
Appearance: Transparent, colorless crystals, efflorescent in dry air.
Solubility: Very soluble in water, practically insoluble in ethanol 96 per cent. It dissolves in its water of crystallization at about 49C.

IDENTIFICATION
A. It decolorizes iodinated potassium iodide solution.
B. To 0.5 ml of solution S (see Tests) add 0.5 ml of water R and 2 ml of silver nitrate solution. A white precipitate is formed which rapidly becomes yellowish and then black.
C. To 2.5 ml of solution S add 2.5 ml of water and 1 ml of hydrochloric acid. A precipitate of sulphur is formed and gas is evolved which gives a blue colour to starch iodate paper.
D. 1 ml of solution S gives reaction of sodium.

TESTS
Solution S: Dissolve 10.0 g in carbon dioxide-free water R prepared from distilled water R and dilute to 100 ml with the same solvent.
Appearance of solution: The freshly prepared solution is clear and colourless.
Dissolve 10.0 g in 50 ml of distilled water, add 1 ml of 0.1 M sodium hydroxide and dilute to 100 ml with the same solvent.
pH: 6.0 to 8.4 for the freshly prepared solution S.
Sulphates and sulphites: Maximum 0.2 per cent.
Sulphides: To 10 ml of solution S add 0.05 ml of a freshly prepared 50 g/l solution of sodium nitroprusside. The solution does not become violet.
Heavy metals: Maximum 10 ppm.

Sodium Thiosulfate FCC Food Grade, US Food Chemical Codex
Sodium Hyposulfite
Na2S2O3-5H2O Formula weight 248.19

DESCRIPTION
Sodium Thiosulfate or Sodium Thiosulphate occurs as large, colorless crystals or as a coarse, crystalline powder. It is deliquescent in moist air and effloresces in dry air at a temperature above 33C. Its solutions are neutral or faintly alkaline to litmus. One gram dissolves in 0.5 mL of water. It is insoluble in alcohol.
Function: Sequestrant; antioxidant.

REQUIREMENTS
Identification
A. Add a few drops of iodine TS to a 1:10 aqueous solution. The color disappears.
B. A 1:20 aqueous solution gives positive tests for Sodium and for Thiosulfate.
Assay: Not less than 99.0% and not more than 100.5% of Na2S2O3 after drying.
Lead: Not more than 2 mg/kg.
Selenium: Not more than 0.003%.
Water: Between 32.0% and 37.0%.

Sodium Thiosulfate Pentahydrate or Sodium Thiosulphate Analytical Reagent
Na2S2O3 . 5H2O
Formula Wt 248.19
CAS Number 10102-17-7

REQUIREMENTS
Assay: 99.5-101.0% Na2S2O3-5H2O
pH of a 5% solution: 6.0-8.4 at 25C

MAXIMUM ALLOWABLE
Insoluble matter: 0.005%
Nitrogen compounds (as N): 0.002%
Sulfate and sulfite (as SO4): 0.1%
Sulfide (S): Passes test.

Anmol Chemicals
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